Your privacy, your choice

We use essential cookies to make sure the site can function. We also use optional cookies for advertising, personalisation of content, usage analysis, and social media.

By accepting optional cookies, you consent to the processing of your personal data - including transfers to third parties. Some third parties are outside of the European Economic Area, with varying standards of data protection.

See our privacy policy for more information on the use of your personal data.

for further information and to change your choices.

You are viewing the site in preview mode

Skip to main content
Fig. 2 | Alzheimer's Research & Therapy

Fig. 2

From: Assessment of the relationship between synaptic density and metabotropic glutamate receptors in early Alzheimer’s disease: a multi-tracer PET study

Fig. 2

Correlation maps of mGluR5 and synaptic density in all regions

Pearson’s correlation coefficients (r) and associated p values were calculated between [18F]FPEB (mGluR5) and [11C]UCB-J (synaptic density) PET DVRs in all regions in participants with (A) Alzheimer’s Disease (n = 15) and (B) normal cognition (n = 12). All voxels in each region were colored uniformly for regions that had an uncorrected p < 0.05 and displayed as an overlay on the MNI template T1 MRI. Abbreviations: AD = Alzheimer’s disease; CN = cognitively normal; DVR = Distribution volume ratio; mGluR5 = metabotropic glutamate receptor subtype 5; PVC = partial volume correction

Back to article page

Alzheimer's Research & Therapy

ISSN: 1758-9193